《伊萨卡》是根据美国作家威廉·萨洛扬（ William Saroyan）1943年的长篇小说《人间喜剧》（The Human Comedy）改编的，故事围绕着居住在加州小镇“伊萨卡”的14岁少年荷马（Homer Macauley）展开，哥哥去欧洲作战后，家中就剩下他来照顾妈妈、姐姐以及4岁的弟弟尤利西斯（Ulysses）。荷马是小镇上的自行车电报送信员，在1942年的那个春夏，他为小镇上的居民送去了无数承载着爱、痛苦、死亡以及希望的消息，也从一个男孩成长为了男子汉。
It tells the story of how Octavio and Adela were born on the same day: 14 April 1931, but in opposing families. Over the next 90 years their lives will intertwine, through intense encounters and misunderstandings, in eight episodes told in sequence shots.
When Danny, a guilt-ridden engineering geologist in transit to her remote Russian assignment survives a mysterious helicopter crash, she must try to escape the harsh environment. But she is not alone.
