The Simpsons' fifteenth season began on Sunday, November 2, 2003, with "Treehouse of Horror XIV". The season contains five hold-over episodes from the season 14 (EABF) production line. The most watched episode had 16.2 million viewers and the least watched had 6.2 million viewers.

本故事讲述一个天网恢恢疏而不漏，邪不能胜正的故事，警察所所长丁探长和当地富商冯大头为了一己之私勾结洋人汉奸倒卖鸦片，为了找寻传说中的宝藏而不惜牺牲无辜的孙家周家两家的性命，更是全然不顾国家危亡，。女探长霍青带着得力助手烟儿来到浦江镇，虽与警察局副所长邢易有诸多误会，但幸好及时说清，三人携手，大破孙家和周家灭门案，揭露了丁探长和冯大头的卖国罪行，所有案件真相大白，坏人也得到了应有的惩罚，而浦江镇也恢复了往日的平静。

Welcome to a world ravaged by explosions of violence, a world without love. Jung, the broken-hearted hero, pursues his quest: reunite with Maria, his lost love, savagely decapitated by Little Jesus. He can count on the support of allies met along his bloody path, encounters that provide an understanding of others, but especially of himself. He also has to deal with his “violent outbreaks,” an incontrollable curse that springs from his murderous soul.

Darkness降临，末日降临，Dean见到了Darkness——Amara，她要毁灭世界来报复上帝。Dean因该隐之印与她有所联系而无法下杀手。这一季诸多配角十分出彩，Crowley与女巫Rowena的剧情线相当值得一看。